CV


Pontifical Catholic University of Chile 2019 - Present

Assistant Professor

Department of Mechanical Engineering

Institute of Biological and Medical Engineering.

Education

Pontifical Catholic University of Chile 2019

Postdoctoral fellow at the Institute of Biological and Medical Engineering.

Stanford University 2014 - December 2018

Ph.D in Mechanical Engineering, Living Matter Laboratory.

University of California, San Francisco March - April 2011

Visiting Scholar

Washington State University January - February 2011

Visiting Scholar

Pontifical Catholic University of Chile

Master of Engineering Science 2010 - 2011

Graduated summa cum laude.

Mechanical Engineering 2005 - 2011

Graduated summa cum laude.

Educational Experience

Pontificia Universidad Católica de Chile, Mechanical Engineering. 2012 - 2014

Instructor: Teaching “Solid Mechanics” and “Product Design Workshop".

Universidad de los Andes March - July 2012

Instructor: teaching “Statics”.

Professional Experience

Wenco S.A. 2012 - 2014

R&D Engineer.

Publications

F. Sahli, P. Perdikaris, E. Kuhl, DE. Hurtado. Multi-fidelity classification using Gaussian processes: accelerating the prediction of large-scale computational models. Computer Methods in Applied Mechanics and Engineering, accepted (2019).

M. Peirlinck, F, Sahli, KL. Sack, JS. Choy, GS. Kassab, JM. Guccione, M. De Beule, P. Segers, E. Kuhl. Using machine learning to characterize heart failure across the scales. Biomechanics and Modeling in Mechanobiology. 2019; doi:10.1007/s10237-019-01190-w.

F. Sahli, JS. Choy, KL. Sack, JM. Guccione, G. Kassab, E. Kuhl. Multiscale characterization of heart failure. Acta Biomaterialia, no. 86 (2019): 66-76

F. Sahli, K. Matsuno, J. Yao, P. Perdikaris, E. Kuhl. Machine learning in drug development: Characterizing the effect of 30 drugs on the QT interval using Gaussian process regression, sensitivity analysis, and uncertainty quantification. Computer Methods in Applied Mechanics and Engineering, no. 348 (2019): 313-333

F. Sahli, A. Sher, J. Yao, E. Kuhl. Predicting critical drug concentrations and torsadogenic risk using a multiscale exposure-response simulator. Progress in Biophysics and Molecular Biology (2019); doi:10.1016/j.pbiomolbio.2018.10.003

F. Sahli, J. Yao, E. Kuhl. Predicting drug-induced arrhythmias by multiscale modeling. International journal for numerical methods in biomedical engineering 34, no. 5 (2018): e2964.

F. Sahli, J. Yao, E. Kuhl. Predicting the cardiac toxicity of drugs using a novel multiscale exposure–response simulator. Computer methods in biomechanics and biomedical engineering 21, no. 3 (2018): 232-246.

F. Sahli, JAB. Zaman, E. Kuhl, SM. Narayan. Interpreting activation mapping of atrial fibrillation: A hybrid computational/physiological study. Annals of biomedical engineering 46, no. 2 (2018): 257-269.

F. Sahli, FA. Concha, DE. Hurtado, E. Kuhl. The importance of mechano-electrical feedback and inertia in cardiac electromechanics. Computer Methods in Applied Mechanics and Engineering, no. 320 (2017): 352-368.

F. Sahli, DE. Hurtado, E. Kuhl. Generating Purkinje networks in the human heart. Journal of Biomechanics no. 49 (2016): 2455-2465.

F. Sahli, J. Cuellar, A. Perez, AJ. Fields, M. Campos, J. Ramos-Grez. Structural parameters determining the strength of the porcine vertebral body affected by tumors. Computer Methods in Biomechanics and Biomedical Engineering 18, no 8 (2015): 890-899.

AJ. Fields, F. Sahli, AG. Rodriguez, and JC. Lotz. Seeing double: a comparison of microstructure, biomechanical function, and adjacent disc health between double-and single-Layer vertebral endplates. Spine 37, no. 21 (2012): E1310-E1317.

A. Hamdan, F. Sahli, R. Richards, and C. Richards. Characterization of a dielectric microdroplet thermal interface material with dispersed nanoparticles. Journal of Nanoparticle Research 14, no. 9 (2012): 1-8.

Pre-prints, Conference Proceedings & Others

F. Sahli, K. Seo, E. Ashley, E. Kuhl. Classifying drugs by their arrhythmogenic risk using machine learning. bioRxiv. doi:10.1101/545863.

F. Sahli, J. Yao, E. Kuhl. A high resolution multiscale model to study drug-induced arrhythmias (2018). World Congress on Computational Mechanics

F. Sahli, FA. Concha, DE. Hurtado, E. Kuhl. The importance of mechano-electrical feedback and inertia in cardiac electromechanics (2017). U.S. National Congress of Computational Mechanics

SM. Narayan, T. Baykaner, F Sahli, E. Kuhl. Terminating atrial fibrillation by cooling the heart. Editorial Commentary in Heart Rhythm. 2016;13:2259-2260

F. Sahli, DE. Hurtado, E. Kuhl. Generating Purkinje networks in the human heart (2016). World Congress of Computational Mechanics.

F. Sahli, J. Cuellar, A. Pérez, M. Campos, J. Ramos-Grez (2011). Estudio mediante elementos finitos de vértebras porcinas afectadas por tumores simulados. X Jornadas de mecánica computacional.

AJ. Fields, F. Sahli, AG. Rodriguez, J. Ramos-Grez, TM. Keaveny, JC. Lotz (2011). Effects of endplate microstructure on biomechanical integrity. New Horizons in intervertebral disc research.

AJ. Fields, F. Sahli, AG. Rodriguez, J. Ramos-Grez, TM. Keaveny, JC. Lotz (2011). Comparison of biomechanical behavior, morphology, and disc health between double-layer and single-layer endplates. Orthopedic Research Society 2012 Annual Meeting.

AJ. Fields, F. Sahli, AG. Rodriguez, J. Ramos-Grez, TM. Keaveny, JC. Lotz (2011). Influence of endplate morphology on biomechanical behavior in double-layer endplates. Orthopedic Research Society 2012 Annual Meeting.

Awards

FONDECYT - Postdoctoral grant: (2019). I obtained funding for my research in drug induced arrhythmias for 3 years.

School of Engineering Postdoctoral Fellowship: (Pontifical Catholic University of Chile, 2019). Funds one year of postdoctoral projects.

Travel award: (Newton Institute). To attend workshop in uncertainty quantification for cardiac models.

CO-PI in XSEDE grant: (2018). We were awarded 650,000 cpu-hours to study drug-induced arrhythmias using high performance computing.

Hyperion innovation excellence award: (2017). For the development of a computational model to predict drug-induced arrhythmias.

Avonni - Industrial Category: (National Innovation Award, Chile, 2015). At Wenco S.A., I developed a crate to export fruits that saves millions of dollars in raw materials.

Stanford School of Engineering Fellowship (2014-2016)

Fulbright-CONICYT Ph.D Fellowship (2014-2018): Fund to complete doctoral studies.

Ismael Valdes Award: (Chilean Institute of Engineers, 2013). Granted to one engineer per school who demonstrates leadership skills, high moral standards and technical preparation.

Mario Hiriart Award: (Pontifical Catholic University of Chile, 2012). Granted to one student of the School of Engineering who combines academic excellence with humanitarian values.

Best Thesis of the Department of Mechanical Engineering: (School of Engineering, Pontifical Catholic University of Chile, 2012).

Honor Roll (School of Engineering, Pontifical Catholic University of Chile, 2005) Scholarship awarded during the first year for maximum score in the mathematics university selection test.

Patents

Light and integrated junction system of the walls of a collapsible container.
United States US20150284135A1, filed March 5, 2015. Inventors: Francisco Sahli, Pedro Chinni.

Bottom of a container that optimizes the use of material.
United States US20150283745A1, filed March 5, 2015. Inventors: Francisco Sahli, Pedro Chinni.

Journal Reviewer

Computer Methods in Biomechanics and Biomedical Engineering.

Applied Mechanics Reviews.

Journal of the Mechanics and Physics of Solids.

Annals of Biomedical Engineering

Computers in Biology and Medicine